The season was extended one week, each team playing 17 games with one bye-week across the 18-week schedule.

2021 Regular Season Results

Date    OpponentResultScoreRecord
9/12vs SeattleL  16-28 0-1
9/19vs LA RamsL  24-27 0-2
9/26at TennesseeL  16-25 0-3
10/3at MiamiW  27-17 1-3
10/11at BaltimoreL  25-31
OT
1-4
10/17vs HoustonW  31-3 2-4
10/24at San FranciscoW  30-18 3-4
10/31vs TennesseeL  31-34
OT
3-5
11/4vs NY JetsW  45-30 4-5
11/14vs JacksonvilleW  23-17 5-5
11/21at BuffaloW  41-15 6-5
11/28vs Tampa BayL  31-38 6-6
12/5at HoustonW  31-0 7-6
12/18vs New EnglandW  27-17 8-6
12/25at ArizonaW  22-16 9-6
1/2vs Las VegasL  20-23 9-7
1/9at JacksonvilleL  11-26 9-8