Due to a mid-season players' strike, the season was divided into a first half and a second half. The division winner of each half played each other in a five-game divisional series. The Cincinnati Reds, despite having the best overall record during the season, finished 2nd in both halves, so did not qualify for the post-season.

1981 Regular Season Results

Date    OpponentResultScoreRecord
4/9at SeattleW  6-2 1-0
4/10at SeattleL  2-10 1-1
4/11at SeattleW  7-4 2-1
4/12at SeattleW  8-6 3-1
4/13vs OaklandL  2-3 3-2
4/14vs OaklandL  2-5 3-3
4/15vs OaklandL  3-5 3-4
4/16vs OaklandL  1-5 3-5
4/17vs MinnesotaW  4-0 4-5
4/18vs MinnesotaL  4-6 4-6
4/20vs SeattleW  6-1 5-6
4/21vs SeattleL  0-3 5-7
4/22vs SeattleW  7-3 6-7
4/24at MinnesotaL  5-7 6-8
4/25at MinnesotaW  6-4 7-8
4/26at MinnesotaW  7-1 8-8
4/26at MinnesotaL  2-5 8-9
4/27at OaklandW  3-2 9-9
4/28at OaklandW  3-1 10-9
4/29at OaklandL  4-6 10-10
4/30vs MilwaukeeL  1-12 10-11
5/1vs MilwaukeeW  8-4 11-11
5/2vs MilwaukeeL  5-8 11-12
5/3vs MilwaukeeL  3-4 11-13
5/4vs NY YankeesL  2-4 11-14
5/5vs NY YankeesW  6-2 12-14
5/6vs NY YankeesL  2-5 12-15
5/7vs NY YankeesW  2-1 13-15
5/8vs DetroitL  1-6 13-16
5/9vs DetroitW  15-1 14-16
5/10vs DetroitW  4-3 15-16
5/12at MilwaukeeW  4-0 16-16
5/13at MilwaukeeW  6-3 17-16
5/14at MilwaukeeW  9-1 18-16
5/15at DetroitL  1-5 18-17
5/16at DetroitL  5-7 18-18
5/17at DetroitW  7-1 19-18
5/18at ClevelandW  7-2 20-18
5/19at ClevelandL  3-7 20-19
5/20at BaltimoreL  3-5 20-20
5/21at BaltimoreW  2-0 21-20
5/22vs Chi. White SoxL  5-9 21-21
5/23vs Chi. White SoxL  4-15 21-22
5/24vs Chi. White SoxL  2-10 21-23
5/25vs TorontoW  2-1 22-23
5/26vs TorontoL  4-8 22-24
5/27vs TorontoL  1-3 22-25
5/30at Chi. White SoxL  0-9 22-26
5/31at Chi. White SoxW  7-4 23-26
5/31at Chi. White SoxL  1-2
10
23-27
6/1at TorontoW  3-0 24-27
6/2at TorontoW  3-0 25-27
6/3at TorontoW  17-6 26-27
6/5vs BaltimoreL  4-6 26-28
6/6vs BaltimoreW  10-0 27-28
6/7vs BaltimoreL  1-4 27-29
6/8vs ClevelandW  10-2 28-29
6/9vs ClevelandW  4-2 29-29
6/10vs ClevelandW  4-3 30-29
6/11vs BostonW  7-2 31-29
8/10at SeattleL  4-5 31-30
8/11at SeattleL  1-4 31-31
8/12at SeattleW  4-1
11
32-31
8/14at OaklandL  2-4
10
32-32
8/15at OaklandL  7-8
13
32-33
8/16at OaklandL  6-7 32-34
8/18vs BaltimoreL  5-6 32-35
8/19vs BaltimoreW  6-3 33-35
8/20vs BaltimoreW  6-2 34-35
8/21vs ClevelandW  12-2 35-35
8/22vs ClevelandW  3-2
10
36-35
8/23vs ClevelandL  3-6 36-36
8/24vs BostonW  8-6 37-36
8/25vs BostonW  8-7
10
38-36
8/27at BaltimoreL  2-6 38-37
8/28at BaltimoreW  9-2 39-37
8/29at BaltimoreL  3-4 39-38
8/30at BaltimoreW  7-1 40-38
8/31at BostonL  1-4 40-39
9/1at BostonW  3-2 41-39
9/2at BostonL  1-3 41-40
9/4at ClevelandW  3-1 42-40
9/5at ClevelandL  2-4 42-41
9/5at ClevelandL  2-4 42-42
9/6at ClevelandL  0-2 42-43
9/7at Kansas CityL  1-7 42-44
9/8at Kansas CityL  3-5 42-45
9/9at Kansas CityL  3-7 42-46
9/11vs TexasL  6-11 42-47
9/12vs TexasL  2-3 42-48
9/13vs TexasW  8-7
12
43-48
9/14vs Kansas CityL  3-4 43-49
9/15vs Kansas CityL  2-3 43-50
9/16vs Kansas CityL  1-3 43-51
9/18at TorontoL  1-5 43-52
9/19at TorontoL  4-6 43-53
9/20at TorontoL  3-6 43-54
9/21vs Chi. White SoxW  6-3 44-54
9/22vs Chi. White SoxW  1-0 45-54
9/23vs Chi. White SoxW  7-3 46-54
9/24vs Chi. White SoxL  1-4 46-55
9/25vs TorontoW  11-5 47-55
9/26vs TorontoW  6-3 48-55
9/27vs TorontoL  3-4 48-56
9/28at Chi. White SoxW  6-0 49-56
9/29at Chi. White SoxW  5-1 50-56
9/30at Chi. White SoxL  3-10 50-57
10/2at TexasL  6-8
10
50-58
10/3at TexasL  0-1 50-59
10/4at TexasW  9-2 51-59