The season was impacted by the ongoing COVID-19 pandemic; the most prominent changes were the cancellation of all preseason games and the postponement and/or rescheduling of multiple games due to positive COVID-19 tests among players and staff. Despite the changes, all 256 regular season games were played within the original 17-week span, with no cancellations.
2020 Regular Season Results | |||||||||||||||||||
| Date | Opponent | Result | Score | OT | Record | ||||||||||||||
| 9/13 | at Atlanta | W | 38-25 | 1-0 | |||||||||||||||
| 9/20 | vs New England | W | 35-30 | 2-0 | |||||||||||||||
| 9/27 | vs Dallas | W | 38-31 | 3-0 | |||||||||||||||
| 10/4 | at Miami | W | 31-23 | 4-0 | |||||||||||||||
| 10/11 | vs Minnesota | W | 27-26 | 5-0 | |||||||||||||||
| 10/25 | at Arizona | L | 34-37 | 5-1 | |||||||||||||||
| 11/1 | vs San Francisco | W | 37-27 | 6-1 | |||||||||||||||
| 11/8 | at Buffalo | L | 34-44 | 6-2 | |||||||||||||||
| 11/15 | at LA Rams | L | 16-23 | 6-3 | |||||||||||||||
| 11/19 | vs Arizona | W | 28-21 | 7-3 | |||||||||||||||
| 11/30 | at Philadelphia | W | 23-17 | 8-3 | |||||||||||||||
| 12/6 | vs NY Giants | L | 12-17 | 8-4 | |||||||||||||||
| 12/13 | vs NY Jets | W | 40-3 | 9-4 | |||||||||||||||
| 12/20 | at Washington | W | 20-15 | 10-4 | |||||||||||||||
| 12/27 | vs LA Rams | W | 20-9 | 11-4 | |||||||||||||||
| 1/3 | at San Francisco | W | 26-23 | 12-4 | |||||||||||||||