The game took place on Monday, September 22, 1975, between the Pittsburgh Pirates and the Philadelphia Phillies at Three Rivers Stadium. The Pirates, who were having a solid season, were looking to solidify their standing in the National League East, while the Phillies were trying to keep their playoff hopes alive. The starting pitchers for the game were Bruce Kison for the Pirates and Tom Underwood for the Phillies. Kison was in the midst of a solid season, looking to build on his 11-11 record, while Underwood, with a 14-12 record, was hoping to provide the Phillies with a much-needed boost. The 1975 season overall had been marked by the dominance of the Cincinnati Reds, also known as the "Big Red Machine", who were in the midst of one of the greatest seasons in baseball history.

The game started off with both teams unable to score in the first inning. The Pirates got on the scoreboard first in the second inning and added three more runs in the fourth inning. The Phillies, on the other hand, were held scoreless until the fifth inning when they managed to score a single run. The Pirates' offense was led by Willie Stargell and Dave Parker, who combined for five hits and six runs batted in. Stargell, in particular, had a big day at the plate, reaching base five times and scoring four runs. The Phillies' offense was largely stifled by Kison and reliever Kent Tekulve, who combined to allow just three runs.

The Phillies made an attempt to come back in the seventh inning, scoring two runs to cut the Pirates' lead to 5-3. However, the Pirates responded with a massive five-run eighth inning, highlighted by a two-run home run by Parker, his 25th of the season, to extend their lead to 11-3. The Phillies were unable to mount a comeback in the ninth inning, and the Pirates secured a comfortable victory.

The Pirates' victory on September 22, 1975, was a key moment in their successful season. They would go on to finish second in the National League East, just 6.5 games behind the division-winning Philadelphia Phillies. Despite their loss in this game, the Phillies would rally to win the division and make the playoffs, but they were defeated by the Cincinnati Reds in the National League Championship Series. The Reds would go on to win the World Series, cementing their status as one of the greatest teams in baseball history. The 1975 season also saw a number of individual accolades, with Joe Morgan of the Reds winning the National League Most Valuable Player award, and Tom Seaver of the New York Mets winning the Cy Young Award.

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