Brayan Peña, a Cuban-born catcher, embarked on his Major League Baseball (MLB) journey after defecting from Cuba in 1999. He began his professional career in the United States with the Atlanta Braves organization. Peña's MLB debut came on May 23, 2005, with the Braves, where he played intermittently over the next few seasons. His time with Atlanta was marked by limited opportunities, as he served primarily as a backup catcher.

In 2008, Peña's career took a new direction when he was claimed off waivers by the Kansas City Royals. It was with the Royals that he found more consistent playing time, spending several seasons as part of their catching rotation. Peña's tenure in Kansas City allowed him to develop his skills both behind the plate and as a switch-hitter, providing the team with flexibility in their lineup.

Peña's journey continued in 2013 when he signed with the Detroit Tigers. During his time with the Tigers, he served as a reliable backup catcher and contributed to the team's success in reaching the postseason. His experience and ability to handle a pitching staff were valuable assets to the Tigers during his stint with the team.

In 2014, Peña joined the Cincinnati Reds, where he enjoyed one of his most productive seasons. He took on a larger role due to injuries within the team, showcasing his ability to handle increased responsibilities. Peña's performance with the Reds solidified his reputation as a dependable catcher capable of stepping up when needed.

Peña's career came full circle when he returned to the Royals in 2016, although his second stint with the team was brief. Throughout his MLB career, Peña was known for his defensive skills, ability to work with pitchers, and his switch-hitting capability, which added depth to the teams he played for.