The season was extended one week, each team playing 17 games with one bye-week across the 18-week schedule.

2021 Regular Season Results

Date    OpponentResultScoreRecord
9/12at TennesseeW  38-13 1-0
9/19vs MinnesotaW  34-33 2-0
9/26at JacksonvilleW  31-19 3-0
10/3at LA RamsW  37-20 4-0
10/10vs San FranciscoW  17-10 5-0
10/17at ClevelandW  37-14 6-0
10/24vs HoustonW  31-5 7-0
10/28vs Green BayL  21-24 7-1
11/7at San FranciscoW  31-17 8-1
11/14vs CarolinaL  10-34 8-2
11/21at SeattleW  23-13 9-2
12/5at ChicagoW  33-22 10-2
12/13vs LA RamsL  23-30 10-3
12/19at DetroitL  12-30 10-4
12/25vs IndianapolisL  16-22 10-5
1/2at DallasW  25-22 11-5
1/9vs SeattleL  30-38 11-6