The season was impacted by the ongoing COVID-19 pandemic; the most prominent changes were the cancellation of all preseason games and the postponement and/or rescheduling of multiple games due to positive COVID-19 tests among players and staff. Despite the changes, all 256 regular season games were played within the original 17-week span, with no cancellations.
2020 Regular Season Results | |||||||||||||||||||
| Date | Opponent | Result | Score | OT | Record | ||||||||||||||
| 9/13 | vs Las Vegas | L | 30-34 | 0-1 | |||||||||||||||
| 9/20 | at Tampa Bay | L | 17-31 | 0-2 | |||||||||||||||
| 9/27 | at LA Chargers | W | 21-16 | 1-2 | |||||||||||||||
| 10/4 | vs Arizona | W | 31-21 | 2-2 | |||||||||||||||
| 10/11 | at Atlanta | W | 23-16 | 3-2 | |||||||||||||||
| 10/18 | vs Chicago | L | 16-23 | 3-3 | |||||||||||||||
| 10/25 | at New Orleans | L | 24-27 | 3-4 | |||||||||||||||
| 10/29 | vs Atlanta | L | 17-25 | 3-5 | |||||||||||||||
| 11/8 | at Kansas City | L | 31-33 | 3-6 | |||||||||||||||
| 11/15 | vs Tampa Bay | L | 23-46 | 3-7 | |||||||||||||||
| 11/22 | vs Detroit | W | 20-0 | 4-7 | |||||||||||||||
| 11/29 | at Minnesota | L | 27-28 | 4-8 | |||||||||||||||
| 12/13 | vs Denver | L | 27-32 | 4-9 | |||||||||||||||
| 12/19 | at Green Bay | L | 16-24 | 4-10 | |||||||||||||||
| 12/27 | at Washington | W | 20-13 | 5-10 | |||||||||||||||
| 1/3 | vs New Orleans | L | 7-33 | 5-11 | |||||||||||||||