The season was extended one week, each team playing 17 games with one bye-week across the 18-week schedule.

2021 Regular Season Results

Date    OpponentResultScoreRecord
9/12at LA RamsL  14-34 0-1
9/19vs CincinnatiW  20-17 1-1
9/26at ClevelandL  6-26 1-2
10/3vs DetroitW  24-14 2-2
10/10at Las VegasW  20-9 3-2
10/17vs Green BayL  14-24 3-3
10/24at Tampa BayL  3-38 3-4
10/31vs San FranciscoL  22-33 3-5
11/8at PittsburghL  27-29 3-6
11/21vs BaltimoreL  13-16 3-7
11/25at DetroitW  16-14 4-7
12/5vs ArizonaL  22-33 4-8
12/12at Green BayL  30-45 4-9
12/20vs MinnesotaL  9-17 4-10
12/26at SeattleW  25-24 5-10
1/2vs NY GiantsW  29-3 6-10
1/9at MinnesotaL  17-31 6-11