The season was extended one week, each team playing 17 games with one bye-week across the 18-week schedule.

2021 Regular Season Results

Date    OpponentResultScoreRecord
9/12at Kansas CityL  29-33 0-1
9/19vs HoustonW  31-21 1-1
9/26vs ChicagoW  26-6 2-1
10/3at MinnesotaW  14-7 3-1
10/10at LA ChargersL  42-47 3-2
10/17vs ArizonaL  14-37 3-3
10/21vs DenverW  17-14 4-3
10/31vs PittsburghL  10-15 4-4
11/7at CincinnatiW  41-16 5-4
11/14at New EnglandL  7-45 5-5
11/21vs DetroitW  13-10 6-5
11/28at BaltimoreL  10-16 6-6
12/12vs BaltimoreW  24-22 7-6
12/20vs Las VegasL  14-16 7-7
12/25at Green BayL  22-24 7-8
1/3at PittsburghL  14-26 7-9
1/9vs CincinnatiW  21-16 8-9