The season was impacted by the ongoing COVID-19 pandemic; the most prominent changes were the cancellation of all preseason games and the postponement and/or rescheduling of multiple games due to positive COVID-19 tests among players and staff. Despite the changes, all 256 regular season games were played within the original 17-week span, with no cancellations.
2020 Regular Season Results | |||||||||||||||||||
| Date | Opponent | Result | Score | OT | Record | ||||||||||||||
| 9/13 | vs Indianapolis | W | 27-20 | 1-0 | |||||||||||||||
| 9/20 | at Tennessee | L | 30-33 | 1-1 | |||||||||||||||
| 9/24 | vs Miami | L | 13-31 | 1-2 | |||||||||||||||
| 10/4 | at Cincinnati | L | 25-33 | 1-3 | |||||||||||||||
| 10/11 | at Houston | L | 14-30 | 1-4 | |||||||||||||||
| 10/18 | vs Detroit | L | 16-34 | 1-5 | |||||||||||||||
| 10/25 | at LA Chargers | L | 29-39 | 1-6 | |||||||||||||||
| 11/8 | vs Houston | L | 25-27 | 1-7 | |||||||||||||||
| 11/15 | at Green Bay | L | 20-24 | 1-8 | |||||||||||||||
| 11/22 | vs Pittsburgh | L | 3-27 | 1-9 | |||||||||||||||
| 11/29 | vs Cleveland | L | 25-27 | 1-10 | |||||||||||||||
| 12/6 | at Minnesota | L | 24-27 | 1-11 | |||||||||||||||
| 12/13 | vs Tennessee | L | 10-31 | 1-12 | |||||||||||||||
| 12/20 | at Baltimore | L | 14-40 | 1-13 | |||||||||||||||
| 12/27 | vs Chicago | L | 17-41 | 1-14 | |||||||||||||||
| 1/3 | at Indianapolis | L | 14-28 | 1-15 | |||||||||||||||