The season was impacted by the ongoing COVID-19 pandemic; the most prominent changes were the cancellation of all preseason games and the postponement and/or rescheduling of multiple games due to positive COVID-19 tests among players and staff. Despite the changes, all 256 regular season games were played within the original 17-week span, with no cancellations.
2020 Regular Season Results | |||||||||||||||||||
| Date | Opponent | Result | Score | OT | Record | ||||||||||||||
| 9/14 | at NY Giants | W | 26-16 | 1-0 | |||||||||||||||
| 9/20 | vs Denver | W | 26-21 | 2-0 | |||||||||||||||
| 9/27 | vs Houston | W | 28-21 | 3-0 | |||||||||||||||
| 10/11 | vs Philadelphia | W | 38-29 | 4-0 | |||||||||||||||
| 10/18 | vs Cleveland | W | 38-7 | 5-0 | |||||||||||||||
| 10/25 | at Tennessee | W | 27-24 | 6-0 | |||||||||||||||
| 11/1 | at Baltimore | W | 28-24 | 7-0 | |||||||||||||||
| 11/8 | at Dallas | W | 24-19 | 8-0 | |||||||||||||||
| 11/15 | vs Cincinnati | W | 36-10 | 9-0 | |||||||||||||||
| 11/22 | at Jacksonville | W | 27-3 | 10-0 | |||||||||||||||
| 12/2 | vs Baltimore | W | 19-14 | 11-0 | |||||||||||||||
| 12/7 | vs Washington | L | 17-23 | 11-1 | |||||||||||||||
| 12/13 | at Buffalo | L | 15-26 | 11-2 | |||||||||||||||
| 12/21 | at Cincinnati | L | 17-27 | 11-3 | |||||||||||||||
| 12/27 | vs Indianapolis | W | 28-24 | 12-3 | |||||||||||||||
| 1/3 | at Cleveland | L | 22-24 | 12-4 | |||||||||||||||