The season was extended one week, each team playing 17 games with one bye-week across the 18-week schedule.

2021 Regular Season Results

Date    OpponentResultScoreRecord
9/12vs JacksonvilleW  37-21 1-0
9/19at ClevelandL  21-31 1-1
9/23vs CarolinaL  9-24 1-2
10/3at BuffaloL  0-40 1-3
10/10vs New EnglandL  22-25 1-4
10/17at IndianapolisL  3-31 1-5
10/24at ArizonaL  5-31 1-6
10/31vs LA RamsL  22-38 1-7
11/7at MiamiL  9-17 1-8
11/21at TennesseeW  22-13 2-8
11/28vs NY JetsL  14-21 2-9
12/5vs IndianapolisL  0-31 2-10
12/12vs SeattleL  13-33 2-11
12/19at JacksonvilleW  30-16 3-11
12/26vs LA ChargersW  41-29 4-11
1/2at San FranciscoL  7-23 4-12
1/9vs TennesseeL  25-28 4-13